Thromb Haemost 1999; 81(03): 466-467
DOI: 10.1055/s-0037-1614499
Letters to the Editor
Schattauer GmbH

Prevalence of Protein C Deficiency in Patients with Cardiovascular Problems in Japan

Toshiyuki Sakata
1   From the National Cardiovascular Center, Laboratory of Clinical Chemistry, Suita, Japan
,
Yoshiaki Katayama
1   From the National Cardiovascular Center, Laboratory of Clinical Chemistry, Suita, Japan
,
Tatsuo Matsuyama
1   From the National Cardiovascular Center, Laboratory of Clinical Chemistry, Suita, Japan
,
Hisao Kato
2   Research Institute, Fujishirodai, Suita, Japan
,
Toshiyuki Miyata
2   Research Institute, Fujishirodai, Suita, Japan
› Author Affiliations
Further Information

Publication History

Received14 August 1998

Accepted after resubmission02 December 1998

Publication Date:
09 December 2017 (online)

 

 
  • References

  • 1 Miyata T, Sakata T, Zheng YZ, Tsukamoto H, Umeyama H, Uchiyama S, Ikusaka M, Yoshioka A, Imanaka Y, Fujimura H, Kambayashi J, Kato H. Genetic characterization of protein C deficiency in Japanese subjects using a rapid and nonradioactive method for single-strand conformational polymorphism analysis and a model building. Thromb Haemost 1996; 76: 302-11.
  • 2 Miyata T, Sakata T, Yasumuro Y, Okamura T, Katsumi A, Saito H, Abe T, Shirahata A, Sakai M, Kato H. Genetic analysis of protein C deficiency in nineteen Japanese families: Five recurrent defects can explain half of the deficiencies. Thromb Res 1998; 92: 181-7.
  • 3 Sakata T, Kario K, Katayama Y, Matsuyama T, Kato H, Miyata T. Analysis of 45 episodes of arterial occlusive disease in Japanese patients with congenital protein C deficiency. Thromb Res. 1999 in press.
  • 4 Miletich J, Sherman L, Broze Jr. G. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 1987; 317: 991-6.
  • 5 Tait RC, Isobel D, Walker ID, Reitsma PH, Islam SIAM, McCall F, Poort SR, Conkie JA, Bertina RM. Prevalence of protein C deficiency in the healthy population. Thromb Haemost 1995; 73: 87-93.