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Vet Comp Orthop Traumatol 2015; 28(06): 417-424
DOI: 10.3415/VCOT-14-11-0173
Original Research
Schattauer GmbH

Influence of a titanium mesh on the management of segmental long bone defects

An experimental study in a canine ulnar model
S. I. Zoi
1   Veterinary Clinic of Larissa, Larissa, Greece
2   Faculty of Veterinary Medicine, University of Thessaly, Clinic of Surgery, Karditsa, Greece
,
S. A. Papadimitriou
3   School of Veterinary Medicine, Faculty of Health Sciences, Thessaloniki, Greece
,
A. D. Galatos
2   Faculty of Veterinary Medicine, University of Thessaly, Clinic of Surgery, Karditsa, Greece
,
N. N. Prassinos
3   School of Veterinary Medicine, Faculty of Health Sciences, Thessaloniki, Greece
,
D. Psalla
3   School of Veterinary Medicine, Faculty of Health Sciences, Thessaloniki, Greece
,
M. Dalstra
4   Faculty of Health Sciences, Aarhus University, Department of Dentistry Health, Section of Orthodontics, Aarhus, Denmark
,
A. Stavropoulos
5   Faculty of Dentistry, Malmö University, Department of Periodontology, Malmö, Sweden
› Author Affiliations
Further Information

Publication History

Received:25 November 2014

Accepted:23 July 2015

Publication Date:
23 December 2017 (online)

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Summary

Objectives: To evaluate the influence of titanium mesh on guided bone regeneration when used, either alone or in combination with autogenous bone block graft, in a canine ulnar model.

Methods: Thirty-two, purpose bred, adult, castrated male Beagles were used, divided into four equal-size groups. A unilateral middiaphyseal ulnar critical-size defect was created in each dog. The ulnar segments were stabilized with a stainless-steel plate and screws. Each defect was managed by: no further treatment (Group A) or by placement of a bone block graft taken from the ipsilateral iliac crest (Group B), or titanium mesh wrapped around the ulna (Group C), or a bone block graft and titanium mesh (Group D). After six months, bone block biopsies were performed and the samples were scanned using micro-computed tomography. Qualitative histological evaluation was performed on two non-decalcified longitudinal sections from each block.

Results: No significant differences in terms of mineralized bone volume were detected between the grafted sites (Groups B and D) or between the non-grafted ones (Groups A and C). The histological evaluation indicated good integration of the bone blocks irrespective of the use of titanium mesh.

Clinical significance: The use of titanium mesh does not influence the amount of bone formation. The canine ulnar critical-size defect model seems to be a reliable model to use in experimental studies.

Keywords

Titanium mesh - guided bone regeneration - osteometry - ulnar model - canine

 

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