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Vet Comp Orthop Traumatol 2011; 24(01): 1-8
DOI: 10.3415/VCOT-10-03-0040
Review Article
Schattauer GmbH

The rationale behind novel bone grafting techniques in small animals

G. R. Ragetly
1   Department of Veterinary Clinical Medicine, University of Illinois, Urbana, Illinois, USA
,
D. J. Griffon
1   Department of Veterinary Clinical Medicine, University of Illinois, Urbana, Illinois, USA
› Author Affiliations
Further Information

Publication History

Received: 17 March 2010

Accepted: 24 June 2010

Publication Date:
19 December 2017 (online)

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Summary

Autograft is considered ideal for grafting procedures, providing osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold. Limitations, however, exist regarding donor site morbidity and graft availability. Although allograft provides an osteoconductive matrix with some osteoinductivity, its availability is limited. To achieve optimal bone graft properties, researchers are developing new materials with the goal of designing synthetics as close to autograft as possible while still facilitating their clinical use. However, the constant evolution of internal fixation stimulates the search for growth factors and cells which could stimulate bone healing.

Keywords

Bone grafting - osteogenesis - allograft - osteoconductive material - bone morphogenetic proteins
 

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