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Synfacts 2006(11): 1185-1185  
DOI: 10.1055/s-2006-949399
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Phosphine Dendrimer-Stabilized Pd Nanoparticles for Suzuki-Miyaura Coupling

Contributor(s): Yasuhiro Uozumi, Toshimasa Suzuka
L. Wu, B.-L. Li, Y.-Y. Huang, H.-F. Zhou, Y.-M. He, Q.-H. Fan*
Institute of Chemistry and Graduate School of the Chinese Academy of Sciences, Beijing, P. R. of China
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Publication History

Publication Date:
24 October 2006 (online)

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Significance

Phosphine dendrimer-stabilized palladium nanoparticles [G-3]-PPh2-Pd were developed. Thus, the dendritic phosphine ligand [G-3]-PPh2 was prepared according to the reported procedures (V. J. Catalano, N. Parodi Inorg. Chem. 1997, 36, 537-541). Reduction of Pd(acac)2 with H2 was carried out in the presence of the [G-3]-PPh2 to give the [G-3]-PPh2-Pd (eq. 2). Suzuki-Miyaura reactions of aryl halides with arylboronic acids were promoted by [G-3]-PPh2-Pd to give the corresponding biaryls in high yield (13 examples: 80-94% yield; eq. 1).