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Synfacts 2011(12): 1272-1272
DOI: 10.1055/s-0031-1289341
DOI: 10.1055/s-0031-1289341
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of (-)-Hodgkinsine B
R. H. Snell, R. L. Woodward, M. C. Willis*
University of Oxford and AstraZeneca, Macclesfield, UK
Further Information
Publication History
Publication Date:
18 November 2011 (online)
Significance
Hodgkinsine B is one of a number of polypyrrolidinoindoline alkaloids present in a range of plants. These natural products have gained considerable interest from the synthetic community due to their highly symmetric structure containing six stereocenters and their vast range of biological activity.