Palladium-Catalyzed Coupling of Thiophenes and Thiazoles
with Arylboronic Acids

S. Kirchberg; S. Tani; K. Ueda; J. Yamaguchi; A. Studer; K. Itami

doi:10.1055/s-0030-1259783

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Synfacts 2011(5): 0537-0537
DOI: 10.1055/s-0030-1259783

Metal-Mediated Synthesis

Palladium-Catalyzed Coupling of Thiophenes and Thiazoles with Arylboronic Acids

Contributor(s): Paul Knochel, Andreas K. Steib
S. Kirchberg, S. Tani, K. Ueda, J. Yamaguchi, A. Studer*, K. Itami*
Westfälische Wilhelms-Universität, Münster, Germany and Nagoya University, Japan

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Publication History

Publication Date:
15 April 2011 (online)

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Significance

A novel palladium-catalyzed oxidative biaryl coupling of thiophenes and thiazoles with arylboronic acids has been disclosed. The new protocol regioselectively yields the C4-arylated products.