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DOI: 10.1055/s-0030-1250464
© Georg Thieme Verlag KG Stuttgart · New York
New Phenylpropanoids and In Vitro α-Glucosidase Inhibitors from Balanophora japonica
Publication History
received June 4, 2010
revised September 26, 2010
accepted September 29, 2010
Publication Date:
26 October 2010 (online)
![](https://www.thieme-connect.de/media/plantamedica/201105/lookinside/thumbnails/10.1055-s-0030-1250464-1.jpg)
Abstract
Five new phenylpropanoids, named balajaponins A–E (1–5), were isolated from Balanophora japonica, along with 24 known compounds. Among them, three hydrolysable tannins (6–8) showed specific in vitro α-glucosidase inhibition, with IC50 values in the range of 1–4 µM. Kinetic analysis revealed that they all acted in a noncompetitive mode.
Key words
Balanophora japonica - Balanophoraceae - phenylpropanoids - hydrolysable tannins - α‐glucosidase inhibitors
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Prof. Li-jiang Xuan
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Shanghai Institute of Materia Medica
Chinese Academy of Sciences
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