A Simple and Practical Method for Large-Scale Acetylation of Alcohols and Diols Using Bismuth Triflate

Abstract

A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed. The acetylation proceeds smoothly in MeCN with as little as 0.1 mol% bismuth triflate in good yields.

Key words

bismuth and compounds - acylation - alcohols - diols

References

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The authors wish to thank an anonymous referee for useful suggestions regarding a possible mechanism.