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Synfacts 2011(10): 1141-1141
DOI: 10.1055/s-0030-1261092
DOI: 10.1055/s-0030-1261092
Polymer-Supported Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Arylation of Heterocycles with a CuO Nanospindle
W. Zhang*, Q. Zeng, X. Zhang, Y. Tian, Y. Yue, Y. Guo, Z. Wang*
Anhui Normal University, Wuhu, China
Further Information
Publication History
Publication Date:
20 September 2011 (online)
Significance
A CuO nanospindle catalyzed the direct arylation of heterocycles 1 with aryl iodides 2 to give the corresponding arylated products 3 in up to 93% yield (21 examples). The catalyst was recovered and reused twice without significant loss of its catalytic activity in the formation of 3a (1st reuse: 91% yield, 2nd reuse: 88% yield).