New Phenylpropanoids and In Vitro α-Glucosidase Inhibitors from Balanophora japonica

Abstract

Five new phenylpropanoids, named balajaponins A–E (1–5), were isolated from Balanophora japonica, along with 24 known compounds. Among them, three hydrolysable tannins (6–8) showed specific in vitro α-glucosidase inhibition, with IC₅₀ values in the range of 1–4 µM. Kinetic analysis revealed that they all acted in a noncompetitive mode.

Key words

Balanophora japonica - Balanophoraceae - phenylpropanoids - hydrolysable tannins - α‐glucosidase inhibitors

References

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