Vet Comp Orthop Traumatol 2008; 21(02): 147-151
DOI: 10.3415/VCOT-07-01-0009
Original Research
Schattauer GmbH

Signalment differences in bone mineral content and bone mineral density in canine appendicular bones

A cadaveric study
K. Lorinson
1   Small Animal Surgical Center Dr. Lorinson, Vienna, Austria
2   Clinical Department of Small Animals and Horses, University of Veterinary Medicine, Vienna, Austria
,
S. Loebcke
3   Institute of Pathology and Forensic Veterinary Medicine, University of Veterinary Medicine, Vienna, Austria
,
M. Skalicky
4   Institute of Pathophysiology, University of Veterinary Medicine, Vienna, Austria
,
S. Grampp
5   Department of Radiodiagnostic, General Hospital Vienna, Vienna, Austria
,
D. Lorinson
1   Small Animal Surgical Center Dr. Lorinson, Vienna, Austria
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 25. Januar 2007

Accepted 12. Mai 2007

Publikationsdatum:
17. Dezember 2017 (online)

Summary

The objective was to determine signalment-related differences in bone mineral content (BMC) and bone mineral density (BMD) in dogs. Unilateral appendicular bones were harvested from 62 canine cadavers. Middiaphyseal regions of interest (ROIs) were scanned using a Hologic® DXA device Braincon, Vienna, Austria). BMC and BMD were calculated within this region. Middle-aged dogs (3 . 10 years) revealed the highest BMC and BMD levels. Mean BMC and BMD were higher in males compared to females. Furthermore, bodyweight of the male dogs was significantly higher compared to the females (P<0.0001). Body weight and bone length were significantly associated with BMC and BMD (P.0.023) in all bones but the radius. These data suggest that BMC and BMD appear to be highest in male large-breed dogs with a body weight greater than 30 kg. These results may help determine risk factors in fracture development and healing.

 
  • References

  • 1 Markel MD, Sielman E, Bodganske JJ. Densito- metric properties of long bones in dogs, as determined by use of dual-energy x-ray absorptio- metry. Am J Vet Res 1994; 55: 1750-1756.
  • 2 Lauten SD, Cox NR, Brawner WR. et al. Use of dual energy x-ray absorptiometry for noninvasive body composition measurements in clinically normal dogs. Am J Vet Res 2001; 62: 1295-1301.
  • 3 Loebcke S. Dual-Energy X-Ray Absorptiometrie der langen Rohrenknochen beim Hund. Thesis 2003, University of Veterinary Medicine Vienna.
  • 4 Trudel G, Koike Y, Dinh L. et al. Thawing of frozen calcaneus bone specimens has no effect on the bone mineral density using dual-energy x-ray absorptiometry: a study in rabbits and humans. Physiol Meas 2005; 26: 769-777.
  • 5 Ferretti JL, Capozza RF, Cointry GR. et al. Gender-related differences in the relationship between densitometric values of whole-body bone mineral content and lean body mass in humans between 2 and 87 years of age. Bone 1998; 22: 683-690.
  • 6 Millis Millis, Groesslinger K. Evaluation of Limb Composition by Dual-Energy X-Ray Absorptio- metry in Dogs 1 Year After Cranial Cruciate Ligament Transection and Stifle Repair. Proceedings of the 13th ECVS Annual Meeting, Prag, Czech Republic 2004; 84-85.
  • 7 Mazess Mazess, Barden HS. Bone density in preme- nopausal women: effects of age, dietary intake, physical activity, smoking, and birth-control pills. Am J Clin Nutr 1991; 53: 132-142.
  • 8 Wilson AK, Bhattacharyya MH, Miller S. et al. Ovariectomy-induced changes in aged beagles: histomorphometry of rib cortical bone. Calcif Tissue Inter 1998; 62: 237-243.
  • 9 Yamaura M, Nakamura T, Nagai Y. et al. Reduced Mechanical Competence of Bone by Ovariectomy and its Preservation with 24R, 25- Dihydroxyvi- tamin D3 Administration in Beagles. Calcif Tissue Inter 1993; 52: 49-56.
  • 10 Ekici H, Sontas BH, Toydemir TS. et al. Effect of prepubertal ovariohysterectomy on bone mineral density and bone mineral content in puppies. Acta Vet Hung 2005; 53: 469-478.
  • 11 Naganathan Naganathan, Sambrook P. Gender differences in volumetric bone density: a study of opposite-sex twins. Osteoporosis International 2003; 14: 564-569.
  • 12 Valdimarsson O, Kristinsson JO, Stefansson SO. et al. Lean mass and physical activity as predictors of bone mineral density in 16- 20-year-old women. J Inter Med 1999; 245: 489-496.
  • 13 Ahlborg HG, Johnell O, Karlsson MK. An age-related medullary expansion can have implications for the long-term fixation of hip prostheses. Acta Orthop Scand 2004; 75: 154-159.
  • 14 Lauten SD, Cox NR, Baker GH. et al. Body composition of growing and adult cats as measured by use of dual energy x-ray absorptiometry. Comp Med 2000; 50: 175-183.