Am J Perinatol 1995; 12(2): 138-142
DOI: 10.1055/s-2007-994426
ORIGINAL ARTICLE

© 1995 by Thieme Medical Publishers, Inc.

Mathematical Modeling of Fetal Organ Growth Using the Rossavik Growth Model: IV. Lung

Toshiyuki Hata, Atsushi Manabe, Naomi Tamaru, Antoine Abu Musa, Kohkichi Hata, Manabu Kitao
  • Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan
Further Information

Publication History

Publication Date:
04 March 2008 (online)

ABSTRACT

Growth of the fetal lung has been monitored by left lung area (LLA), right lung area (RLA), and total lung area (TLA) from 14 to 41 weeks menstrual age in 116 normal Japanese fetuses. Growth of the fetal heart and chest has also been monitored by heart area (HA) and chest area (CA), respectively. Growth curves for these parameters have been determined by using a Rossavik growth model [p = c (t)k+s (t)]. R2 values of 95.3%, 90.3%, 89.0%, 88.7%, and 92.1% were obtained for CA, HA, LLA, RLA, and TLA, respectively. Variability analysis indicated a progressive increase in variability with fetal age for these five parameters. Variability data were used with the growth curve models to determine standard curves for these parameters. These standard curves provide a superior means for evaluating the normal fetal lung growth in the fetus and for identifying pulmonary hypoplasia in utero.