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Horm Metab Res 1987; 19(12): 653-655
DOI: 10.1055/s-2007-1011901
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Correlation of Daily Urinary Excretion of Met-Enkephalin-Like Immunoreactivity and Epinephrine in Men

T. Yanase, H. Nawata, K. Kato, H. Ibayashi
  • Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan
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Publication History

1986

1987

Publication Date:
14 March 2008 (online)

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Summary

To investigate the source of urinary Met-enkephalin-like immunoreactivity (MELI), 24-h urinary excretion of MELI and catecholamines (CAs) were examined in normal subjects and patients with tuberculous Addison's disease.

MELI was present in urine and 24-h urinary excretion of MELI averaged 813.8±446.9 ng/day in normal subjects (N=33, Mean ± SD). 24-h urinary excretion of MELI in normal subjects significantly showed positive correlation with 24-h urinary epinephrine (E) (R=0.392, P<0.05) but no correlation with that of norepinephrine (NE) or dopamine (DA). In two patients with tuberculous Addison's disease, 24-h urinary excretion of MELI and that of E were significantly lower than those of normal subjects.

These results indicate that the main source of urinary MELI may be adrenal medulla.

Key-Words

Met-Enkephalin - Epinephrine - Urine - Correlation

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