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J Reconstr Microsurg 1987; 4(1): 33-37
DOI: 10.1055/s-2007-1006960
ORIGINAL ARTICLE

© 1987 by Thieme Medical Publishers, Inc.

Polytetrafluoroethylene Microprosthesis in the Arterial System of the Rat

Luis Padilla, Armando Valle, Hugo Carrillo, Mauricio Di Silvio, Mauricio Contreras, Fernando Viniegra, Rodolfo Sanchez, Javier Fajer
  • Experimental Surgery Service, Microsurgery Clinic, and Department of Surgery Universidad Nacional Autónoma de México, Caoyoacán, Mexico
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Publication History

Accepted for publication 1987

Publication Date:
08 March 2008 (online)

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ABSTRACT

The experimental behavior of a 1-mm internal diameter (i.d.) polytetrafluoroethylene (PTFE) microprosthesis, as a substitute for an abdominal aortic segment in the rat, was reviewed. Fifty Wistar rats were divided into four groups: Group I - 12 rats with autotransplant of an abdominal aortic segment (AAS); Group II - 12 rats with allotransplant of an AAS obtained from Long-Evans rats; Group III - 12 rats with xeno-transplant of an AAS taken from rabbit femoral arteries; and Group IV - 14 rats with substitution of an AAS by a 1-mm i.d. PTFE microprosthesis. The rats were sacrificed at different time intervals ranging from five to 360 days, with previous aortography.

In Group I, there was a 100 percent patency at a mean of 152.41 days; in Group II, a 91.6 percent patency at a mean of 100.08 days; in Group III, an 83.3 percent patency with a 75 percent aneurysmal dilation at a mean of 107.58 days; in Group IV, a 71.42 percent patency with two anastomotic aneurysms at a mean of 105 days (P < 0.05, chi square) between Groups I and IV, autotransplant vs. PTFE).

The 1-mm PTFE microprosthesis placed in the arterial system of the rat proved to be a reliable alternative for microvascular substitution.

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