Biotransformation of a [14CH3]-2-Methylaminobenzophenone by Plant Cell Cultures

A. Baumert; Zs Rosza; W. Schliemann; J. R. Lewis; D. Gröger

doi:10.1055/s-2006-962630

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Planta Med 1987; 53(1): 90-92
DOI: 10.1055/s-2006-962630

Full Papers

Biotransformation of a [¹⁴CH₃]-2-Methylaminobenzophenone by Plant Cell Cultures

A. Baumert¹ , Zs. Rosza² , W. Schliemann¹ , J. R. Lewis³ , D. Gröger¹

¹Institut für Biochemie der Pflanzen, Akademie der Wissenschaften der DDR, Weinberg 3, DDR-4050 Halle (Saale), German Democratic Republic.
²Pharmacognosy Department, Medical University, Szeged, Hungary.
³Chemistry Department, University of Aberdeen, Scotland, U.K.

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Publication History

1986

Publication Date:
24 January 2007 (online)

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Abstract

2-[¹⁴ C]-Methylamino-2′,4′-dimethoxy-6′-hydroxybenzophenone (4) was synthesized and administered to Ruta graveolens cell suspension cultures. Compound 4 was not incorporated into acridone alkaloids but glucosylated giving 7. This reaction takes place also in cell suspension cultures of Adhatoda vasica and Peganum harmala.