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Planta Med 1988; 54(3): 243-245
DOI: 10.1055/s-2006-962417
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© Georg Thieme Verlag Stuttgart · New York

Alkaloids and Phenolics of Colchicum cilicicum 1,2

N. Sütlüpinar3 , A. Husek4 , H. Potěšilová4 , S. Dvořáčková4 , V. Hanuš5 , P. Sedmera6 , V. Šimánek4
  • 3Department of Pharmacognosy, University of Istanbul, Istanbul, Turkey.
  • 4Institute of Medical Chemistry, Palacký University, 775 15 Olomouc, Czechoslovakia.
  • 5The J. Heyrovský Institute of Physical Chemistry and Electrochemistry, Czechoslovak Academy of Sciences, Prague, Czechoslovakia.
  • 6Institute of Microbiology, Czechoslovak Academy of Sciences, Prague, Czechoslovakia.
1 Part CI in the series: Substances from the Plant of the Subfamily Wurmbaeoideae and their Derivatives; Part C: Phytochemistry 26, 1031 (1987).2 Dedicated to Professor Jiří Slavík, Brno. on the occasion of his 65th birthday.
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Publication History

1987

Publication Date:
24 January 2007 (online)

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Abstract

The distributions of the alkaloids colchicine, 2-demethylcolchicine, 3-demethylcolchicine, demecolcine, 2-demethyldemecolcine, and 3-demethyldemecolcine in the corms, stems, leaves, flowers, and seeds of Colchicum cilicicum were analysed by HPLC. In addition, the alkaloids cornigerine, N-formyl-N-deacetylcolchicine, N-methyl-demecolcine, β-lumicolchicine, γ-lumicolchicine, β-lumidemecolcine, γ-lumidemecolcine, and N-ethoxycarbonyldemecolcine were identified, the last named being reported for the first time from a Colchicum species. The flavones luteolin and apigenin were isolated and benzoic, 2-hydroxy-6-methoxybenzoic, and vanillic acids were also detected.