Molekulare kardiovaskuläre Bildgebung

Zusammenfassung

In der kardiovaskulären Diagnostik bestehen trotz intensiver und langjähriger Forschung im Bereich der bildgebenden Diagnostik nahezu unverändert große Herausforderungen. Im Speziellen sind dies Fragestellungen im Zusammenhang mit der Diagnostik einer vermuteten oder bestehenden koronaren Herzkrankheit oder deren Folgen (Myokardinfarkt, Herzinsuffizienz). Neben morphologisch orientierten bildgebenden Verfahren, haben bereits heute funktionelle Verfahren einen diagnostischen Stellenwert, hingegen sind molekulare Bildgebungsverfahren noch in der Entwicklung. Dieser Beitrag gibt einen Überblick der klinisch-diagnostischen Herausforderungen in der kardiovaskulären Medizin sowie über Lösungsansätze durch neu zu entwickelnde molekulare Bildgebungsmodalitäten.

Abstract

Although huge and long-lasting research efforts have been spent on the development of new diagnostic techniques investigating cardiovascular diseases, still fundamental challenges exist; the main challenge being the diagnosis of a suspected or known coronary artery disease or its consequences (myocardial infarction, heart failure etc.). Beside morphological techniques, functional imaging modalities are available in clinical diagnostic algorithms, whereas molecular cardiovascular imaging techniques are still under development. This review summarizes clinical-diagnostical challenges of modern cardiovascular medicine as well as the potential of new molecular imaging techniques to face these.

Schlüsselwörter

molekulare Bildgebung - kardiovaskuläre Erkrankungen - PET - SPECT - Plaque - Arteriosklerose - Herzrhythmusstörungen

Key words

molecular imaging - cardiovascular diseases - PET - SPECT - plaque - atherosclerosis - tachyarrhythmias

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