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Synthesis 2004(2): 237-240  
DOI: 10.1055/s-2003-44386
PAPER
© Georg Thieme Verlag Stuttgart · New York

The Formation of β-Lactam Derivatives through the Reaction of Dibenzoyl­acetylene and Aryl Isocyanates in the Presence of Trivalent Phosphorus Nucleophiles

Issa Yavari*, Abdolali Alizadeh
Department of Chemistry, University of Tarbiat Modarres, P.O. Box 14115-175, Tehran, Iran
Fax: +98(21)8006544; e-Mail: isayavar@yahoo.com;
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Publikationsverlauf

Received 27 August 2003
Publikationsdatum:
18. Dezember 2003 (online)

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Abstract

An effective route to novel β-lactams is described. This involves reaction of dibenzoylacetylene and phenyl isocyanate or phenylsulfonyl isocyanate in the presence of trivalent phosphorus nucleophiles.

Key words

triphenylphosphine - trialkyl phosphates - dibenzoylacetylene - aryl isocyanate - β-lactams

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