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Synthesis 2002(7): 0901-0905
DOI: 10.1055/s-2002-28512
DOI: 10.1055/s-2002-28512
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of New Fluorine Containing Triazolo- and Tetrazolopyrimidines
Further Information
Received
5 February 2002
Publication Date:
14 May 2002 (online)
Publication History
Publication Date:
14 May 2002 (online)
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Abstract
The reaction of 1,1,1-trifluoro-4-(sulfonyl)-but-3-ene-2,2-dioles 1a,b with corresponding aminoazoles was investigated. A new simple and efficient way for the regioselective synthesis of 5-CF3 or 7-CF3 triazolo- and tetrazolopyrimidines is described.
Key words
cycloaddition - heterocycles - triazolopyrimidine - tetrazolopyrimidine - sulfones
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