Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 2001; 2001(9): 1415-1416
DOI: 10.1055/s-2001-16793
DOI: 10.1055/s-2001-16793
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Simple Way to 1H-Benzo[i,j][2,7]naphthyridines
Further Information
Publication History
Publication Date:
28 August 2001 (online)
Heating of 2,2-dioxoisothiazolo[5,4,3-d,e]quinolines (available from 3-nitroanilines in a simple three-step synthesis) with an excess of bis-functionalized methylene CH acids in the presence of K2CO3 as a base afforded 1H-benzo[i,j][2,7]naphthyridines in good yields.
2,2-dioxoisothiazolo[5,4,3-d,e]quinolines - 1H-benzo[i,j][2,7]naphthyridines - nucleophilic aromatic substitution - condensation - cyclization