J Reconstr Microsurg 2001; 17(6): 439-444
DOI: 10.1055/s-2001-16359
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

A New Animal Model for Tissue Preservation

Sühan Ayhan1 , Osman Latifoğlu1 , Ömür Ataoğlu2 , Kenan Atabay1
  • 1Department of Plastic and Reconstructive Surgery, Gazi University Medical School, Ankara, Turkey
  • 2Department of Pathology, Gazi University Medical School, Ankara, Turkey
Further Information

Publication History

Publication Date:
31 December 2001 (online)

ABSTRACT

In vivo preservation of tissues may exist as a problem in experimental and clinical research. Adipose tissue, nerves, and vessels are the tissues that are usually preserved in vivo for future use or for the evaluation of results in experimental research. Limited volume and difficult conditions in such areas in animal models usually create disappointing results, because of the difficulty in distinguishing the experimental from the surrounding tissues; the insufficiency of the volume of space; and the lack of compliance in animals. A new rat model for in vivo preservation studies is described. A muscular pocket designed between the external and internal oblique muscles is a good choice as an animal model for tissue preservation in plastic surgery research.

REFERENCES

  • 1 Moscona R, Shoshani O, Lichtig H, Karnieli E. Viability of adipose tissue injected and treated by different methods: an experimental study in the rat.  Ann Plast Surg . 1994;  33 500
  • 2 Smahel J. Experimental implantation of adipose tissue fragments.  Br J Plast Surg . 1989;  42 207
  • 3 Eppley B L, Sidner R A, Platis J M, Sadove A M. Bioactivation of free-fat transfers: a potential new approach to improving graft survival.  Plast Reconstr Surg . 1992;  90 1022
  • 4 Goldberg I, Knight K R, Mahoney J E, O'Brien B M. A biochemical and histological comparison of vascularized and free fat grafts in the rabbit.  Ann Plast Surg . 1993;  30 334
  • 5 Kononas T C, Bucky L P, Hurley C, May Jr W J. The fate of suctioned and surgically removed fat after reimplantation for soft-tissue augmentation: a volumetric and histologic study in the rabbit.  Plast Reconstr Surg . 1993;  91 763
  • 6 Viterbo F, Marques M, Valente M. Fat-tissue injection versus graft: experimental study in rabbits.  Ann Plast Surg . 1994;  33 184
  • 7 May Jr W J. Comparative study of survival of autologous tissue taken and transplanted by different techniques (discussion).  Plast Reconstr Surg . 1990;  85 387
  • 8 Mikus J L, Koufman J A, Kilpatrick S E. Fate of liposuctioned and purified autologous fat injections in the canine vocal fold.  Laryngoscope . 1995;  105 17
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