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Synlett 2001; 2001(6): 0848-0850
DOI: 10.1055/s-2001-14614
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Intramolecular Heck Coupling of Alkenyl 3-Iodoindole-2-carboxamide Derivatives

Lidwine Chacun-Lefèvre* , Benoît Joseph, Jean-Yves Mérour
  • *Institut de Chimie Organique et Analytique, UMR-CNRS 6005, Université d'Orléans, BP 6759, 45067 Orléans Cedex 2, France; Fax (33) 2-38-41-70-81; E-mail: jean-yves.merour@univ-orelans.fr
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Publication Date:
31 December 2001 (online)

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Ethyl 2-(1-oxo-1,2,3,4,5,10-hexahydroazepino[3,4-b]indol-5-yliden)acetate derivative 1 a has been synthesised in good yield from indole-2-carboxylic acid 2 via a stoichiometric intramolecular Heck reaction.

indole - palladium - cross-coupling - Heck - cyclisation

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