Download PDF
Synlett 2000; 2000(8): 1077-1091
DOI: 10.1055/s-2000-6732
account
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Alkyl 2-Substituted 3-(Dimethylamino)propenoates and Related Compounds - Versatile Reagents in Heterocyclic Chemistry

Branko Stanovnik* , Jurij Svete
  • *Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia; Fax + 3 86(61)1 25 82 20; E-mail: branko.stanovnik@uni-lj.si
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Alkyl 2-substituted 3-(dimethylamino)propenoates and related compounds, masked α-formyl-α-amino- and α-formyl-α-hydroxy acid derivatives, available in one step from 2-substituted acetic acid derivatives by treatment with amide acetals, represent a useful synthetic tool for a simple preparation of various heterocyclic systems and aryl- and heteroaryl substituted amino acid derivatives. On the other hand, 3-(dimethylamino)propenoates can also serve as reagents for the protection of amino group, e.g. in peptide synthesis.

3-(dimethylamino)propenoates - heterocyclic systems - synthesis - reagents - amino acids

      >