Download PDF
Synlett 2000; 2000(6): 0890-0892
DOI: 10.1055/s-2000-6698
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Bisabolane Sesquiterpenes: Synthesis of (R)-(+)-Sydowic Acid and (R)-(+)-Curcumene Ether

Stefano Serra*
  • *Dip. di Chimica del Politecnico, Centro CNR per la Chimica delle Sostanze Organiche Naturali, Via Mancinelli 7, 20131 Milano, Italy; Fax 39 2 23993080; E-mail: lab545@dept.chem.polimi.it
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

A stereoselective synthesis of (R)-(+)-sydowic acid 1 and (R)-(+)-curcumene ether 2 is described. The enantiomerically pure tetrahydropyran building block (R)-(-)-cinenic acid 5 is obtained by resolution of the racemic acid. The aromatic moiety is constructed using a benzoannulation reaction as a key step. An easy way to the title compounds in racemic form is also reported.

annulations - cyclizations - sesquiterpenes - tetrahydropyran - phenols

      >