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Synlett 2000; 2000(5): 0728-0730
DOI: 10.1055/s-2000-6600
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Enzymatic Synthesis of Galβ1 → 3 GlcNAc Derivatives Utilising a Phosphorylase from Bifidobacterium bifidum 20082

Erzsébet Farkas* , Joachim Thiem, Frédéric Krzewinski, Stéphane Bouquelet
  • *Institut für Organische Chemie, Universität Hamburg, Martin-Luther-Platz 6, D-20146 Hamburg, Germany; Fax + 49(0)4 04 28 38 43 25; E-mail: thiem@chemie.uni-hamburg.de
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Publication Date:
31 December 2000 (online)

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The stereo- and regiospecific synthesis of Galβ1 → 3 GlcNAc derivatives was achieved in up to 57% yield employing the β-1 → 3-galactosyl-N-acetylhexosamine phosphorylase from Bifidobacterium bifidum DSM 20082.

carbohydrates - enzymatic glycosylation - phosphorylase - Bifidobacterium bifidum - Galβ1 → 3 GlcNAc

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