Download PDF
Synlett 1997; 1997(1): 97-99
DOI: 10.1055/s-1997-687
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Palladium-catalyzed asymmetric carbonylative coupling of iodophenol with norbornene

Christophe Moinet, Jean-Claude Fiaud*
  • *Laboratoire des Réactions Organiques Sélectives, URA CNRS 1497, ICMO, Université Paris-Sud, 91405 Orsay, France, E-mail fiaud@icmo.u-psud.fr
Further Information

Publication History

Publication Date:
22 March 2004 (online)

  PDF Download  Permissions and Reprints All articles of this category

Palladium-catalyzed three component condensation of norbornene, 2-iodophenol and carbon monoxide (1 atm.) affords two regioisomers according to the sequence of insertions (carbon monoxide and norbornene) into the arylpalladium initial complex. The distribution of products can be controlled upon variation of the phosphine ligand, the temperature and the concentration of reagents. Low enantioselectivities (up to 26%ee) in both products have been recorded through the use of chiral phosphine ligands.

palladium(0)-catalyzed arylation - carbonylation - norbornene - enantioselectivity

      >