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Synlett 1997; 1997(6): 697-698
DOI: 10.1055/s-1997-3273
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A Novel Approach for the Synthesis of Purine Acyclonucleosides Using 9-D-Ribitylpurines as a Chiral Pool

Kosaku Hirota1 , Yasunari Monguchi2 , Hironao Sajiki2 , Yukio Kitade3
  • 1Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502, Japan, FAX +81-58-237-5979
  • 2Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502, Japan
  • 3Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido, 501-11, Japan
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Publication History

Publication Date:
31 December 2000 (online)

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Facile syntheses of L-eritadenine (8a), (2S,3R)-9-(2,3,4-trihydroxybutyl)purines (4a and 4b), and (2S,3S)-9-(2,3,4-trihydroxybutyl)adenine (6a) were achieved by using 9-D-(2,3-O-isopropylideneribityl)purines (1a and 1b) as a chiral pool

purine acyclonucleosides - 9-D-ribitylpurines as a chiral pool

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