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Synlett 1995; 1995(10): 1031-1032
DOI: 10.1055/s-1995-5166
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An Iminophosphorane-Mediated Efficient Synthesis of 2,5-Disubstituted-4,5-dihydroimidazoles

Pedro Molina* , Isidora Díaz, Alberto Tárraga
  • *Departamento de Química Orgánica, Facultad de Química, Universidad de Murcia, Campus de Espinardo, E-30071, Murcia, Spain
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Publication Date:
31 December 2000 (online)

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A one-flask synthesis of 2,5-disubstituted-4,5-dihydroimidazoles based on the aza-Wittig reaction of β-acetoxyazides with isocyanates or acyl chlorides followed by treatment with ammonia is described.

aza-Wittig reaction - iminophosphoranes - carbodiimides - imidoyl chlorides

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