Download PDF
Synlett 1993; 1993(4): 293-295
DOI: 10.1055/s-1993-22437
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Stereocontrolled Synthesis of Optically Active Plagiospirolides A and B

Nobuo Kato* , Xue Wu, Hideyuki Nishikawa, Hitoshi Takeshita
  • *Institute of Advanced Material Study, 86, Kyushu University, Kasuga-koen, Kasuga, Fukuoka 816, Japan
Further Information

Publication History

Publication Date:
19 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Optically-active plagiospirolides A and B (C35-terpenoids) were synthesized by Diels-Alder reaction between independently synthesized sesquiterpenoids (diplophyllolide A and diplophyllin) and a 5-8-5-membered tricyclic diterpenic hydrocarbon prepared from a CrCl2-mediated condensate of (3S)-benzyloxy-1-iriden-7-al and (3R)-7-chloro-1-iridene. This biogenetic type total synthesis established the absolute configuration of plagiospirolides A and B.

      >