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Synlett 1990; 1990(9): 547-548
DOI: 10.1055/s-1990-21162
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Amino Alcohol Mediated Enantioselective Addition of 2-Phenylethynylzinc Bromide to Aldehydes

G. M. Ramos Tombo* , E. Didier, B. Loubinoux
  • *Ciba-Geigy AG, Agricultural Division, CH-4002 Basel, Switzerland
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Publication Date:
08 March 2002 (online)

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Optically active secondary phenylalkynyl alcohols were obtained in good yields and selectivities via (-)-N-methyl-ephedrine lithium salt mediated addition of 2-phenylethynylzinc bromide to alkyl and aryl aldehydes.

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