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Semin intervent Radiol 2024; 41(02): 135-143
DOI: 10.1055/s-0044-1786813
Review Article

Local Treatment of Desmoid Tumors: An Update

Lawrence Han Hwee Quek
1   Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore
2   Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
,
Lester Wai Mon Chan
2   Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
3   Division of Musculoskeletal Tumor, Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore
,
Uei Pua
1   Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore
4   Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Abstract

Desmoid tumors (DTs) are rare fibroblastic proliferations, characterized by infiltrative growth and a propensity for local recurrence. Traditional strategies such as surgery, radiotherapy, and chemotherapy are the mainstays of treatment, each with its limitations and associated risks. The trend in DT management leans toward a “wait-and-see” strategy, emphasizing active surveillance supported by continuous MRI monitoring. This approach acknowledges the unpredictable nature of the disease, and a multidisciplinary management of DT requires a nuanced approach, integrating traditional therapies with emerging interventional techniques. This review highlights the emerging role of minimally invasive interventional radiological technologies and discusses interventional radiology techniques, including chemical, radiofrequency, microwave, cryoablation, and high-intensity focused ultrasound ablations as well as transarterial embolization.

Keywords

desmoid tumor - radiofrequency ablation - microwave ablation - transarterial chemoembolization - interventional radiology


Publication History

Article published online:
10 July 2024

© 2024. Thieme. All rights reserved.

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