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Thromb Haemost 1986; 56(02): 238
DOI: 10.1055/s-0038-1661650
Letter to the Editor
Schattauer GmbH Stuttgart

Failure of L - Asparaginase to Decrease Protein C - A Possible Rebound Phenomenon

M G Cappellato
University of Padua Medical School, Institute of Medical Semeio-tics, Second Chair of Medicine and Department of Pediatrics, Padua, Italy
,
A Lazzaro
University of Padua Medical School, Institute of Medical Semeio-tics, Second Chair of Medicine and Department of Pediatrics, Padua, Italy
,
A Rosolen
University of Padua Medical School, Institute of Medical Semeio-tics, Second Chair of Medicine and Department of Pediatrics, Padua, Italy
,
L Zanesco
University of Padua Medical School, Institute of Medical Semeio-tics, Second Chair of Medicine and Department of Pediatrics, Padua, Italy
,
A Girolami
University of Padua Medical School, Institute of Medical Semeio-tics, Second Chair of Medicine and Department of Pediatrics, Padua, Italy
› Author Affiliations
Further Information

Publication History

Received 28 May 1986

Accepted 24 July 1986

Publication Date:
20 July 2018 (online)

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  • References

  • 1 Barbui T, Finazzi G, Viganò S, Mannucci PM. L-Asparaginase lowers protein C antigen. Thromb Haemostas 1984; 52: 216
    PubMedGoogle Scholar
  • 2 Priest JR, Ramsay NK C, Steinherz PG et al. A syndrome of thrombosis and hemorrhage complicating L-Asparaginase therapy for childhood acute lymphoblastic leukemia. J Pediatr 1982; 100: 984-989
    CrossrefPubMedGoogle Scholar
  • 3 Cappellato MG, Rosolen A, Zanesco L, Girolami A. Clotting complications of L-Asparaginase therapy in children with ALL. Letter to the Editors. Blut 1986; 52: 377-378
    CrossrefPubMedGoogle Scholar
  • 4 Pitney WR, Phadke KP, Dean S. Antithrombin III deficiency during asparaginase therapy. Lancet 1980; 1: 493-494
    PubMedGoogle Scholar
  • 5 Vellenga E, Broekmans AW, Kluft C. Thrombotic complications during L-Asparaginase related to Protein C deficiency. Thromb Haemostas 1985; 53: 443
    PubMedGoogle Scholar
  • 6 Dal Bo Zanon R, Fornasiero L, Boscaro M, Cappellato G, Fabris F, Girolami A. Increased factor VIII associated activities in Cushing’s syndrome: a probable hypercoagulable state. Thromb Haemostas 1982; 47: 116-117
    PubMedGoogle Scholar