Platelet Aggregation under Hypocalcaemic Conditions

• References

• 1 Tohgi H, Takahashi H, Watanabe K, Kuki H, Shirasawa Y. Development of large platelet aggregates from small aggregates as determined by laser-light scattering: effects of aggregant concentration and antiplatelet medication. Thromb Haemost 1996; 75: 0389-0393
• 2 Packham MA, Kinlough-Rathbone RL, Mustard JF. Thromboxane A₂ causes feedback amplification involving extensive thromboxane A₂ formation on close contact of human platelets in media with a low concentration of ionized calcium. Blood 1987; 70: 0647-0651
• 3 Falcon CR, Cattaneo M, Ghidoni AC, Mannucci PM. The in vitro production of thromboxane B₂ by platelets of diabetic patients is normal at physiological concentrations of calcium. Thromb Haemost 1993; 70: 0389-0392
• 4 Menys VC, Belcher PR, Noble MIM, Drossos GE, Pillai R, Westaby S. Impaired platelet aggregation after cardiopulmonary bypass in man: enhancement of collagen-induced aggregation in whole blood and plasma by adrena-line ex vivo. Clin Sci 1995; 88: 0269-0275
• 5 Menys VC, Smith CCT, Belcher PR, Pillai R. The influence of aspirin on the proaggregatory action of adrenaline after cardiopulmonary bypass in man. Thrombosis Research 1995; 06: 0377-0380