PDF herunterladen
Thromb Haemost 1962; 08(01): 056-066
DOI: 10.1055/s-0038-1655412
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

A Method for Measuring Antithrombin[*]

Acke Hallén
1   Coagulation Laboratory (Head: Assistant Professor Inga Marie Nilsson) of the Department of Medicine (Head: Professor Jan Waldenstrom), University of Lund, Allmänna Sjukhuset, Malmö, Sweden
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
14. Mai 2019 (online)

  als PDF herunterladen  Lizenzen und Reprints

Summary

A method is described for measuring antithrombin II and III for routine clinical use. The conditions of the test are well defined and the test measures a comparatively higher percentage of the total AT capacity of the plasma than methods hitherto available and gives results in AT units.

* This investigation was supported by grants from the Swedish Medical Research Council given to I. M. Nilsson and from the Faculty of Medicine, University of Lund.


 

  • Literatur

  • 1 Astrup T, Darling S. Measurement and properties of antithrombin.. Acta physiol. scand. 1942; 4: 293
    CrossrefPubMedGoogle Scholar
  • 2 Biggs R, Macfarlane R. C. Human blood coagulation.. Sec. Edition Scientific Publications.; Blackwell, Oxford.: 1957: 360
    Google Scholar
  • 3 Blombäck B, Blombäck M. Purification of bovine and human fibrinogen.. Arkiv för kemi 1956; 10: 415
    PubMedGoogle Scholar
  • 4 Fell C, Ivanovic N, Johnsson A. S, Seegers W. H. Differentiation of plasma antithrombin activities.. Proc. Soc. exp. Biol. 1954; 85: 199
    CrossrefPubMedGoogle Scholar
  • 5 Greep J. M. Antithrombine en aandoeningen van het pancreas.. Thesis.; Utrecht: 1958
    Google Scholar
  • 6 Greep J. M, Loeliger E. A, Roos J. Progressive antithrombin time according to Innerfield and it’s relation to acute pancreatitis.. Thromb. Diath. haem. 1960; 5: 149
    PubMedGoogle Scholar
  • 7 Howell W. H, Holt E. Two new factors in blood coagulation — heparin and proantithrombin.. Amer. J. Physiol. 1918; 47: 328
    PubMedGoogle Scholar
  • 8 Jorpes E, Vrethammar T, Öhman B, Blombäck B. On the assay of thrombin preparations.. J. Pharm. Pharmacol. 1958; 10: 561
    CrossrefPubMedGoogle Scholar
  • 9 Jürgens J. Neue Bestimmungsmethoden und Bedeutung der Antithrombine für die Klinik.. Klin. Wschr. 1957: 303
    Google Scholar
  • 10 Loeliger A, Hers J. F. Ph. Chronic antithrombinaemia (antithrombin V) with haemorrhagic diathesis in a case of rheumatoid arthritis with hypergammaglobulinaemia.. Thromb. Diath. haem. 1957; 1: 499
    PubMedGoogle Scholar
  • 11 Lyttleton J. W. The antithrombin activity of human plasma.. Biochem. J. 1954; 58: 8
    CrossrefPubMedGoogle Scholar
  • 12 Lyttleton J. W. The antithrombin activity of heparin.. Biochem. J. 1954; 58: 15
    CrossrefPubMedGoogle Scholar
  • 13 Magnusson S. N-terminal glycine analysis for the determination of the proteolytic activity of thrombin.. Thromb. Diath. haem. 1960; 4: 167
    PubMedGoogle Scholar
  • 14 Marbet R, Winterstein A. Bedeutung und Nachweis von plasmaantithrombin.. Ärztl. Lab. 1956; 2: 319
    PubMedGoogle Scholar
  • 15 Martin C. J, Golubow J, Axelrod A. E. The hydrolysis of carbobenzoxy-L-tyrosine p-nitrophenyl ester by various enzymes.. J. biol. Chem. 1959; 234: 1718
    CrossrefPubMedGoogle Scholar
  • 16 Monkhouse F. C, France E. S, Seegers W. H. Studies on the antithrombin and heparin cofactor activities of a fraction adsorbed from plasma by aluminium hydroxide.. Circulat. Res. 1955; 3: 397
    CrossrefPubMedGoogle Scholar
  • 17 Niewiarowski S, Kowalski E. Formation of an antithrombin-like anticoagulant during proteolysis of fibrinogen.. Bull. academie polon. Sci. 1957; 5: 169
    PubMedGoogle Scholar
  • 18 Nilsson I. M, Blombäck M, von Francken I. On an inheridet autosomal haemorrhagic diathesis with antihaemophilic globulin (AHG) deficiency and prolonged bleeding time.. Acta med. scand. 1957; 159: 35
    PubMedGoogle Scholar
  • 19 Nilsson I. M, Wenckert A. Demonstration of a heparin-like anticoagulant in normal blood.. Acta med. scand. 1954; 150: 297
    PubMedGoogle Scholar
  • 20 Quick A. J. The Physiology and Pathology of Hemostasis.. Kimton; London: 1951: 164
    Google Scholar
  • 21 Seegers W. H. A new plasma antithrombin reaction.. Arch. Biochem. 1952; 36: 484
    CrossrefPubMedGoogle Scholar
  • 22 Seegers W. H, Miller K. D, Andrews E. B, Murphy R. C. Fundamental interactions and the effect of storage, ether, adsorbants and blood clotting on plasma antithrombin activity.. Amer. J. Physiol. 1952; 169: 700
    PubMedGoogle Scholar
  • 23 Sherry S, Troll W. The action of thrombin on synthetic substrates.. J. biol. Chem. 1954; 208: 95
    CrossrefPubMedGoogle Scholar
  • 24 Shinowara G. Y, Buckley D. J. Isolation of antithrombin + globulin from human blood plasma.. Thromb. Diath. haem. 1960; 4: 17
    PubMedGoogle Scholar
  • 25 Sokal G. Die Bestimmung der Antithrombinaktivitäten der Plasmas.. Acta haemat. (Basel) 1955; 14: 34
    CrossrefPubMedGoogle Scholar
  • 26 Verstraete M, Vermylen C. Antithrombin I activity.. Thromb. Diath. haem. 1959; 3: 640
    PubMedGoogle Scholar
  • 27 Volkert M. Studies on the antithrombincontent of the blood and it’s relation to heparin.. Acta physiol.; scand.: suppl. 15 1942
    Google Scholar
  • 28 Wilson J. Quantitative studies on antithrombin.. Proc. Soc. exp. Biol. (N. Y.) 1940; 43: 676
    CrossrefPubMedGoogle Scholar
  • 29 Witte S, Dirnberger P. Die getrennte Bestimmung von Thrombininhibitor und Antithrombin.. Schweiz.; med. Wschr.: 1954: 800
    Google Scholar