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Thromb Haemost 1971; 25(01): 013-020
DOI: 10.1055/s-0038-1654275
Originalarbeiten – Original Articles – Travaux Originaux
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The Induction of the Release Reaction in Human Blood Platelets by Close Cell Contact

P Massini
1   Theodor Kocher Institute, University of Berne
,
E. F Lüscher
1   Theodor Kocher Institute, University of Berne
› Author AffiliationsMiss M. Schneider gave competent technical assistance. The liquid scintillation counters of the institutes for forensic medicine and for medical chemistry at Berne were used. This work was supported by the “(Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung”.
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Publication History

Publication Date:
28 June 2018 (online)

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Summary

When blood platelets are centrifuged at elevated pH they release serotonin. This reaction is similar to the release reaction which makes part of the complex called viscous metamorphosis. The experiments support the hypothesis that contact between platelets forms the stimulus which initiates the release reaction.

 

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