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Thromb Haemost 1987; 58(04): 964-965
DOI: 10.1055/s-0038-1646037
Original Article
Schattauer GmbH Stuttgart

Hypothyroidism Leads to More Small-Sized Platelets in Circulation

J J van Doormaal
*   The Division of Clinical Endocrinology, Department of Internal Medicine, University of Groningen, Groningen, The Netherlands
,
J van der Meer
**   The Division of Haematology, Department of Internal Medicine, University of Groningen, Groningen, The Netherlands
,
H R Oosten
*   The Division of Clinical Endocrinology, Department of Internal Medicine, University of Groningen, Groningen, The Netherlands
,
M R Halie
**   The Division of Haematology, Department of Internal Medicine, University of Groningen, Groningen, The Netherlands
,
H Doorenbos
*   The Division of Clinical Endocrinology, Department of Internal Medicine, University of Groningen, Groningen, The Netherlands
› Author Affiliations
Further Information

Publication History

Received 03 December 1986

Accepted after revision 20 June 1987

Publication Date:
29 June 2018 (online)

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Summary

The effect of induced hypothyroidism on platelet count and platelet volume distribution was studied in twelve athyreotic patients, After a two weeks withdrawal of triiodothyronine supplementation, platelet count and the ratio between platelet and red cell count were increased in all patients. Furthermore, mean platelet volume was declined and platelet distribution width was risen. Thus, hypothyroidism appears to increase the number of circulating platelets, especially the smaller ones.

Keywords

Platelet count - Platelet volume distribution - Hypothyroidism
 

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