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Nervenheilkunde 2007; 26(11): 1018-1026
DOI: 10.1055/s-0038-1626956
Original- und Übersichtsarbeiten - Original and Review Articles
Schattauer GmbH

Gedächtnisprozesse bei obstruktivem Schlafapnoe-Syndrom vor und unter CPAP-Therapie

Memory processes of obstructive sleep apnoea syndrome before and under CPAP therapy
A. Büttner
1   Heinrich-Mann-Klinik, Neurologie und Neurorehabilitation, Bad Liebenstein
2   Klinik Ambrock, Klinik für Pneumologie, Hagen
3   Universität Witten-Herdecke, Witten
,
R. Alnabary
2   Klinik Ambrock, Klinik für Pneumologie, Hagen
,
K. H. Rühle
2   Klinik Ambrock, Klinik für Pneumologie, Hagen
3   Universität Witten-Herdecke, Witten
› Author Affiliations
Further Information

Publication History

Publication Date:
19 January 2018 (online)

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Zusammenfassung

Patienten, die am obstruktiven Schlafapnoe-Syndrom (OSAS) erkrankt sind, leiden unter anderem an einer Beeinträchtigung der Daueraufmerksamkeit und vermutlich auch unter einer Einschränkung ihrer Gedächtnisprozesse und kognitiver Funktionen. In dieser Studie sollen die Gedächtnisprozesse bei OSAS-Patienten mittels Zahlen-Verbindungs-Test (ZVT) und Benton-Test untersucht werden. Insgesamt nahmen 50 Patienten mit obstruktivem Schlafapnoe-Syndrom teil. Sie wurden mittels ZVT und Benton- Test vor Therapieeinleitung und nach 3-tägiger nCPAP-Therapie untersucht. Die OSAS-Patienten wurden anhand ihrer klinischen Diagnose (ICD-10) ausgewählt. Dazu erfolgte eine Polysomnographie nach den Kriterien der DGSM zur Diagnosestellung. Die Überprüfung der Gedächtnisprozesse ergab sowohl beim ZVT als auch beim Benton-Test signifikante Unterschiede (p < 0,001) zwischen Gesunden und OSAS-Patienten. Bereits unter 3-tägiger nCPAP-Therapie verbesserte sich die Gedächtnisleistung der Patienten in den beiden Testverfahren signifikant (p < 0,001 für alle Parameter), das heißt die Gedächtnisprozesse sind somit bei Schlafapnoe-Patienten deutlich eingeschränkt. Im Therapieverlauf ergab sich eine deutliche Verbesserung der Gedächtnisleistung. Die nCPAP-Therapie ist daher die kausale Therapie zur Beseitigung der obstruktiven Ereignisse.

Summary

Patients with obstructive sleep apnea syndrome (OSAS) among other symptoms suffer from an impairment of continuous attention, and presumably also from limited memory processes and cognitive functions. In this study, the memory processes of OSAS patients shall be analyzed employing the Number Connection Test (ZVT) and Benton Test. 50 patients with obstructive sleep apnea syndrome took part in this study. Before starting therapy and after 3 days of nCPAP therapy, these patients were tested with ZVT and Benton Test. The OSAS patients were selected according to their clinical diagnosis (ICD-10). For this purpose, a polysomnography according to the criteria of the DGSM was carried out to arrive at a diagnosis. The testing of memory processes, both for the ZVT and the Benton Test, revealed highly significant differences (p < 0.001) between healthy persons and OSAS patients. Already after 3 days of nCPAP therapy, the patients’ memory capacity in both testing procedures improved to a highly significant degree (p < 0.001 for all parameters). The tests showed that the memory processes of sleep apnea patients are noticeably reduced. In the course of therapy, the improvement of memory capacity was obvious. nCPAP therapy is the causal therapy to counteract the obstructive events.

Schlüsselwörter

Obstruktives Schlafapnoe-Syndrom - Gedächtnisprozesse - nCPAP

Keywords

Obstructive sleep apnea syndrome - memory processes - nCPAP
 

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