J Pediatr Infect Dis 2007; 02(04): 183-192
DOI: 10.1055/s-0035-1557047
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Japanese encephalitis

Viroj Wiwanitkit
a   Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
› Author Affiliations

Subject Editor:
Further Information

Publication History

09 November 2006

20 March 2007

Publication Date:
28 July 2015 (online)

Abstract

Japanese encephalitis (JE) is an important mosquito-borne infection. As a zoonosis, JE cannot be eradicated, but reduction of the human disease burden can be achieved through routine childhood vaccination in endemic countries, which is a low cost, high benefit measure. This article will review the worldwide epidemiology, vector transmission, genetics and molecular biology of JE, as well as present the pathophysiology, clinical manifestations and complications, diagnosis, treatment and prevention of JE.