Thorac Cardiovasc Surg 2015; 63(02): 139-145
DOI: 10.1055/s-0034-1387819
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Factors Affecting Anatomical Changes after Endovascular Abdominal Aortic Aneurysm Repair

Keun-Myoung Park
1   Division of Vascular Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
,
Dong-Ik Kim
1   Division of Vascular Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
,
Young-Wook Kim
1   Division of Vascular Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
,
Young-Soo Do
2   Department of Radiology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
,
Hong Suk Park
2   Department of Radiology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
,
Kwang Bo Park
2   Department of Radiology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
› Author Affiliations
Further Information

Publication History

16 March 2014

22 June 2014

Publication Date:
05 September 2014 (online)

Abstract

Background The primary goal of endovascular aneurysm repair (EVAR) is to prevent death from aneurysm rupture. Regression of aortic sac size is believed to be a marker for success after EVAR. This study analyzes the changes in aneurysm sac size and the factors affecting sac regression after EVAR.

Patients and Methods We retrospectively reviewed 121 patients with abdominal aortic aneurysm (AAA) who underwent elective treatment with EVAR at our institution from January 2005 to December 2011. In this study, 17 of the 121 patients were excluded due to loss during follow-up or for not having undergone a postoperative computed tomographic (CT) scan, and 3 patients were excluded due to an isolated iliac artery aneurysm. CT scans were scheduled at months 1, 6, and 12, and annually thereafter. Aneurysm size was defined by the minor axis on the largest axial cut of the aneurysm on a two-dimensional CT scan. Sac regression was defined as a reduction in the diameter of more than 5 mm.

Results Sac regression was observed during follow-up in 39 of the 101 patients. There was 1 regression in 87 patients (1%) at 1 month, 18 in 62 patients at 6 months (29%), 26 regressions in 44 patients (59%) at 12 months, and 18 regressions in 34 patients (53%) at 24 months. After multivariate analysis, the absence of endoleaks was the only factor associated with sac regression (hazard ratio, 3.620; confidence interval, 1.692–7.747; p = 0.001).

Conclusion Sac regression over 5 mm is associated with current or previous endoleaks after EVAR. Continued surveillance is necessary in all patients after EVAR to prevent late complications.

 
  • References

  • 1 Prinssen M, Verhoeven EL, Buth J , et al; Dutch Randomized Endovascular Aneurysm Management (DREAM) Trial Group. A randomized trial comparing conventional and endovascular repair of abdominal aortic aneurysms. N Engl J Med 2004; 351 (16) 1607-1618
  • 2 Greenberg RK, Deaton D, Sullivan T , et al. Variable sac behavior after endovascular repair of abdominal aortic aneurysm: analysis of core laboratory data. J Vasc Surg 2004; 39 (1) 95-101
  • 3 May J, White GH, Yu W, Waugh RC, Stephen MS, Harris JP. A prospective study of changes in morphology and dimensions of abdominal aortic aneurysms following endoluminal repair: a preliminary report. J Endovasc Surg 1995; 2 (4) 343-347
  • 4 Rhee RY, Eskandari MK, Zajko AB, Makaroun MS. Long-term fate of the aneurysmal sac after endoluminal exclusion of abdominal aortic aneurysms. J Vasc Surg 2000; 32 (4) 689-696
  • 5 Schunn CD, Krauss M, Heilberger P, Ritter W, Raithel D. Aortic aneurysm size and graft behavior after endovascular stent-grafting: clinical experiences and observations over 3 years. J Endovasc Ther 2000; 7 (3) 167-176
  • 6 Haider SE, Najjar SF, Cho JS , et al. Sac behavior after aneurysm treatment with the Gore Excluder low-permeability aortic endoprosthesis: 12-month comparison to the original Excluder device. J Vasc Surg 2006; 44 (4) 694-700
  • 7 Broker HS, Foteh KI, Murphy EH , et al. Device-specific aneurysm sac morphology after endovascular aneurysm repair: evaluation of contemporary graft materials. J Vasc Surg 2008; 47 (4) 702-706 , discussion 707
  • 8 Hogg ME, Morasch MD, Park T, Flannery WD, Makaroun MS, Cho JS. Long-term sac behavior after endovascular abdominal aortic aneurysm repair with the Excluder low-permeability endoprosthesis. J Vasc Surg 2011; 53 (5) 1178-1183
  • 9 Schanzer A, Greenberg RK, Hevelone N , et al. Predictors of abdominal aortic aneurysm sac enlargement after endovascular repair. Circulation 2011; 123 (24) 2848-2855
  • 10 Kaladji A, Cardon A, Abouliatim I, Campillo-Gimenez B, Heautot JF, Verhoye JP. Preoperative predictive factors of aneurysmal regression using the reporting standards for endovascular aortic aneurysm repair. J Vasc Surg 2012; 55 (5) 1287-1295
  • 11 Chaikof EL, Blankensteijn JD, Harris PL , et al; Ad Hoc Committee for Standardized Reporting Practices in Vascular Surgery of The Society for Vascular Surgery/American Association for Vascular Surgery. Reporting standards for endovascular aortic aneurysm repair. J Vasc Surg 2002; 35 (5) 1048-1060
  • 12 Bertges DJ, Chow K, Wyers MC , et al. Abdominal aortic aneurysm size regression after endovascular repair is endograft dependent. J Vasc Surg 2003; 37 (4) 716-723
  • 13 Koole D, Moll FL, Buth J , et al; European Collaborators on Stent-Graft Techniques for Aortic Aneurysm Repair (EUROSTAR). Annual rupture risk of abdominal aortic aneurysm enlargement without detectable endoleak after endovascular abdominal aortic repair. J Vasc Surg 2011; 54 (6) 1614-1622
  • 14 Wolf YG, Hill BB, Rubin GD, Fogarty TJ, Zarins CK. Rate of change in abdominal aortic aneurysm diameter after endovascular repair. J Vasc Surg 2000; 32 (1) 108-115
  • 15 Broeders IA, Blankensteijn JD, Gvakharia A , et al. The efficacy of transfemoral endovascular aneurysm management: a study on size changes of the abdominal aorta during mid-term follow-up. Eur J Vasc Endovasc Surg 1997; 14 (2) 84-90
  • 16 Jim J, Rubin BG, Geraghty PJ, Criado FJ, Sanchez LA. Outcome of endovascular repair of small and large abdominal aortic aneurysms. Ann Vasc Surg 2011; 25 (3) 306-314
  • 17 Sandford RM, Bown MJ, Sayers RD, Fishwick G, London NJ, Nasim A. Endovascular abdominal aortic aneurysm repair: 5-year follow-up results. Ann Vasc Surg 2008; 22 (3) 372-378
  • 18 Verhoeven BA, Waasdorp EJ, Gorrepati ML , et al. Long-term results of Talent endografts for endovascular abdominal aortic aneurysm repair. J Vasc Surg 2011; 53 (2) 293-298
  • 19 van Marrewijk CJ, Fransen G, Laheij RJ, Harris PL, Buth J. EUROSTAR Collaborators. Is a type II endoleak after EVAR a harbinger of risk? Causes and outcome of open conversion and aneurysm rupture during follow-up. Eur J Vasc Endovasc Surg 2004; 27 (2) 128-137
  • 20 Hong C, Heiken JP, Sicard GA, Pilgram TK, Bae KT. Clinical significance of endoleak detected on follow-up CT after endovascular repair of abdominal aortic aneurysm. AJR Am J Roentgenol 2008; 191 (3) 808-813
  • 21 Cho DM, Park KM, Yang SS , et al. Natural History of Type II Endoleaks after Endovascular Aneurysm Repair in Abdominal Aortic Aneurysm. Korean Journal of Vascular and Endovascular Surgery 2011; 27 (4) 162
  • 22 Lu Q, Feng J, Yang Y , et al. Treatment of type I endoleak after endovascular repair of infrarenal abdominal aortic aneurysm: success of fibrin glue sac embolization. J Endovasc Ther 2010; 17 (6) 687-693
  • 23 Burbelko M, Kalinowski M, Heverhagen JT , et al. Prevention of type II endoleak using the AMPLATZER vascular plug before endovascular aneurysm repair. Eur J Vasc Endovasc Surg 2014; 47 (1) 28-36
  • 24 Bailey MA, Sohrabi S, Flood K , et al. Calcium channel blockers enhance sac shrinkage after endovascular aneurysm repair. J Vasc Surg 2012; 55 (6) 1593-1599
  • 25 Raux M, Cochennec F, Becquemin JP. Statin therapy is associated with aneurysm sac regression after endovascular aortic repair. J Vasc Surg 2012; 55 (6) 1587-1592