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Aktuelle Neurologie 2013; 40(06): 309-314
DOI: 10.1055/s-0033-1349100
Originalarbeit
© Georg Thieme Verlag KG Stuttgart · New York

Idiopathisches Parkinson-Syndrom und Melanom: erhöhte Koinzidenz und Zusammenhang mit L-Dopa?

Parkinson’s Disease and Melanoma: Is There an Increased Incidence of their Joint Occurrence under L-Dopa Therapy?
S. Michelmann
1   Klinik und Poliklinik für Dermatologie und Venerologie Universitätsklinikums Hamburg-Eppendorf
,
I. Moll
1   Klinik und Poliklinik für Dermatologie und Venerologie Universitätsklinikums Hamburg-Eppendorf
,
C. Buhmann
2   Ambulanzzentrum - Bereich Neurologie, Universitätsklinikum Hamburg-Eppendorf
,
M. O. Koch
3   Neurologie Toggenburg, Wattwil/Schweiz
,
U. Hauswirth
4   Dermatologie Toggenburg, Wattwil/Schweiz
› Author Affiliations
Further Information

Publication History

Publication Date:
14 August 2013 (online)

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Idiopathisches Parkinson-Syndrom und Melanom: erhöhte Koinzidenz und Zusammenhang mit L-Dopa?Aktuelle Neurologie 2013; 40(04): e59-e59
DOI: 10.1055/s-0033-1355378

Zusammenfassung

Der Zusammenhang zwischen Idiopathischen Parkinson-Syndrom (IPS), L-Dopa-Therapie und malignem Melanom wirft weiterhin Fragen auf. Aus diesem Grund wurde von uns eine Studie mit 712 Parkinson-Patienten aus der Klinik und Poliklinik für Neurologie des Universitätsklinikum Hamburg-Eppendorf durchgeführt, die einerseits zeigte, dass IPS-Patienten formal statistisch ein 1-bis zu 4-fach erhöhtes Melanomrisiko haben und andererseits, dass eine L-Dopa-Therapie die Entstehung eines Melanoms nicht ursächlich zu fördern scheint.

Abstract

The relationship between Parkinson's disease (PD), L-dopa therapy and melanoma is still a topic of some controversy. For this reason we have conducted a study with 712 PD patients of the Department of Neurology in the University Hospital Hamburg-Eppendorf. It showed, on the one hand, that PD patients have statistically a 4-times increased risk to develop a melanoma while, on the other hand, that an L-dopa therapy does not promote the development of melanoma.

Schlüsselwörter

IPS und Melanom - IPS - Melanom - L-Dopa

Keywords

Parkinson’s disease and melanoma - Parkinson’s disease - melanoma - L-dopa
 

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