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Semin intervent Radiol 2013; 30(01): 039-048
DOI: 10.1055/s-0033-1333652
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Transhepatic Therapies for Metastatic Uveal Melanoma

David J. Eschelman
1   Thomas Jefferson University Hospital
2   Division of Interventional Radiology
3   Department of Radiology
,
Carin F. Gonsalves
1   Thomas Jefferson University Hospital
2   Division of Interventional Radiology
3   Department of Radiology
,
Takami Sato
4   Department of Medical Oncology, Kimmel Cancer Center, Philadelphia, Pennsylvania
› Author Affiliations
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Publication History

Publication Date:
27 February 2013 (online)

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Abstract

Despite successful treatment of the primary tumor, uveal melanoma has a propensity to metastasize to the liver. Prognosis is poor due to the very aggressive nature of these tumors. Because systemic therapies are relatively ineffective and patient survival correlates to disease control in the liver, locoregional therapies provide a means of prolonging survival. We review various techniques including chemoembolization, immunoembolization, radioembolization, arterial fotemustine infusion, and hepatic perfusion for the treatment of liver metastases from uveal melanoma.

Keywords

uveal melanoma - liver metastases - chemoembolization - immunoembolization - radioembolization
 

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