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DOI: 10.1055/s-0032-1305218
Glukokortikoidtherapie in der Rheumatologie – welche Dosis ist optimal?
Glucocorticoids in rheumatic diseases – what is the optimal dose?Publication History
12 April 2012
26 June 2012
Publication Date:
29 August 2012 (online)
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Zusammenfassung
Glukokortikoide sind von hohem Wert in der Behandlung von Patienten mit rheumatischen Erkrankungen. Die Ziele der Glukokortikoid-Therapie variieren für die unterschiedlichen Indikationen von Symptomkontrolle bis zur Modifizierung des Krankheitsverlaufes und zur Immunmodulation. Selbst nach 60-jähriger Erfahrung mit Glukokortikoid-Therapien gibt es noch viele offene Fragen hinsichtlich optimaler Therapiestrategien. Mit Blick auf die begrenzte Evidenzlage werden optimale Dosierungen für entzündlich rheumatische Krankheiten diskutiert.
Abstract
Glucocorticoids (GCs) have been an invaluable tool in the treatment of patients with rheumatic diseases. The aims of GC therapy vary for different indications from symptom management to disease-modification and immunmodulation. Even after 60 years of GC use, there is still a lack of knowledge concerning optimal therapeutic strategies with GCs. Taking this into account, optimal dosage schedules for inflammatory rheumatic diseases are discussed.
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