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Semin Neurol 2010; 30(4): 365-372
DOI: 10.1055/s-0030-1267280
© Thieme Medical Publishers

Treatment of Acute Immune-mediated Neuropathies: Guillain-Barré Syndrome and Clinical Variants

Benson H. Sederholm1
  • 1Department of Pharmacy Services, Department of Pharmacotherapy University of Utah College of Pharmacy, University of Utah Hospital, Salt Lake City, Utah
Further Information

Publication History

Publication Date:
12 October 2010 (online)

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ABSTRACT

The author reviews current treatment approaches for the management of acute immune-mediated peripheral neuropathies, including the Guillain-Barré syndrome together with the clinical variants, which are acute inflammatory demyelinating polyradiculoneuropathy, acute motor axonal neuropathy, acute motor and sensory axonal neuropathy, and the Fisher syndrome. A summary of clinical evidence for drug therapies is provided, with additional recommendations for commonly used treatment modalities including a focus on the approach to using intravenous immune globulin and plasma exchange therapy.

KEYWORDS

Guillain-Barré syndrome - acute inflammatory demyelinating polyradiculoneuropathy - acute motor axonal neuropathy - acute motor and sensory axonal neuropathy - Fisher syndrome - intravenous immune globulin - plasma exchange

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Benson H SederholmPharm.D. B.C.P.S. 

University of Utah Hospital, 50 N. Medical Drive

Room A-050, Salt Lake City, UT 84132

Email: Benson.Sederholm@hsc.utah.edu

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