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Exp Clin Endocrinol Diabetes 1999; 107(1): 85-88
DOI: 10.1055/s-0029-1212079
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Acute reserpine treatment alters the catecholamine, glucocorticoid and opioid response to walking exercise in sheep

K. Pierzchala-Koziec, J. Niezgoda, D. Wrońska-Fortuna, S. Bobek, E. Wieczorek
  • Dept. of Animal Physiology, University of Agriculture, Cracow, Poland
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Publication History

Publication Date:
14 July 2009 (online)

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Summary

The aim of the study was to examine the effects of reserpine on the plasma levels of adrenaline, noradrenaline, Cortisol and alpha-neoendorphin in sheep under control conditions and during walking exercise. One hour of walking (5 km/h) caused a significant increase in both catecholamines and Cortisol between 10 and 30 min of stress, and transiently decreased the level of alpha-neoendorphin at the same time. Reserpine at the dose of 0.3 mg/kg i.v. given before stress significantly lowered the basal levels of all tested parameters. A combination of the reserpine and walking exercise significantly attenuated the stress-induced changes in the plasma level of measured hormones.

Key words

Reserpine - hormones - stress - sheep

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