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Exp Clin Endocrinol Diabetes 1990; 96(6): 325-327
DOI: 10.1055/s-0029-1211028
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

11β-Hydroxyandrostenedione in Human Amniotic Fluid

R. Hampl, J. Šulcová, A. Zwinger, L. Stárka
  • Research Institute of Endocrinology (Director: MUDr. K. Vondra, Dr. Sc.), and Institute of Care for Child and Mother (Director: Prof. MUDr. J. Presl, Dr. Sc.), Prague/Czechoslovakia
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Publication History

1989

Publication Date:
16 July 2009 (online)

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Summary

11β-Hydroxyandrostene-3,17-dione (11β-hydroxyandrostenedione), a potential marker for prenatal diagnosis of CAH, has been for the first time determined in amniotic fluid obtained from 68 women who later delivered children without endocrine disorders. Its concentration averaged 0.96 ± 0.31 (S.D.) (range 0.48—1.85) nmol/1 and did not depend on the fetal sex. There was mild, insignificant increase of these values along with duration of pregnancy.

Key words

11β-Hydroxandrostenedione - Amniotic fluid