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DOI: 10.1055/s-0029-1210714
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York
Somatomedin-C in Active and Successfully Treated Acromegaly
Publication History
1987
Publication Date:
16 July 2009 (online)
Summary
Sm-C concentrations serum were found significantly different in either active acromegaly or following successful treatment with pituitary adenomectomy. Although after normalization of serum GH the Sm-C levels sometimes exceeded the normal range no overlap was found between both groups.
Exceptionally two acromegalic patients showed elevated Sm-C levels in spite of normal GH values. Likewise, a high Sm-C concentration was found in one patient suspective of ectopic GH secretion with only moderately elevate serum GH.
Sm-C determinations are judged as a good adjunct to usual diagnostic methods which in special cases of acromegaly can be even superior to measurements of serum GH.
Key words
Somatomedin-C - Acromegaly