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Exp Clin Endocrinol Diabetes 1986; 88(4): 112-114
DOI: 10.1055/s-0029-1210584
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Increased Urinary Antidiuretic Hormone Excretion by Imipramine

V. N. Puri
  • Central Drug Research Institute (Director: M. M. Dhar), Lucknow/India
Further Information

Publication History

1985

Publication Date:
16 July 2009 (online)

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Summary

Seven normal healthy individuals and ten depressive patients treated with imipramine (75 mg orally) were evaluated for their urinary ADH profile. It was observed that imipramine treated patients excreted higher amounts of urinary ADH (10.6 ± 0.83 mU/hr) as compared to the control subjects (2.6 ± 0.35mU/hr) (P < 0.01). Blood pressure in both groups was within the normal range.

Key words

Imipramine - ADH - Blood pressure

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