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Exp Clin Endocrinol Diabetes 1986; 87(3): 349-352
DOI: 10.1055/s-0029-1210567
DOI: 10.1055/s-0029-1210567
Short Communication
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York
Effect of Antiandrogens on the Hypothalamic Gamma-Aminobutyric Acid (GABA) and Glutamate Contents of the Indian Palm Squirrel (Funambulus pennanti, Wroughton)
Further Information
Publication History
1985
Publication Date:
16 July 2009 (online)
Summary
Intramuscular administration of 20 mg/kg flutamide (Flut) or 50 mg/kg of cyproterone acetate (CPA) daily for a period of three weeks significantly elevated the hypothalamic GABA content. CPA is found to decrease the hypothalamic glutamate level while Flut elevated it. Both, Flut and CPA reduced the hypothalamic weight.
Key words
Hypothalamus - GABA - Glutamate - Antiandrogens