Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000011.xml
Dtsch Med Wochenschr 2008; 133(48): 2527-2529
DOI: 10.1055/s-0028-1100952
DOI: 10.1055/s-0028-1100952
Kommentar | Commentary
Intensivmedizin
© Georg Thieme Verlag KG Stuttgart · New York
Hydrokortison auf der Intensivstation: Wer sollte behandelt werden und wann? [1]
Hydrocortisone in intensive care medicine: who should be treated and when?Further Information
Publication History
eingereicht: 12.6.2008
akzeptiert: 1.9.2008
Publication Date:
19 November 2008 (online)
Schlüsselwörter
Hydrokortison - Nebennierenrindeninsuffizienz - septischer Schock - Sepsis
Keywords
hydrocortisone - adrenal insufficiency - septic shock - sepsis
1 Herrn Prof. Dr. Dr. h. c. Klaus Peter zum 70. Geburtstag gewidmet.
Literatur
- 1 Annane D, Maxime V, Ibrahim F, Alvarez J C, Abe E, Boudou P. Diagnosis of adrenal insufficiency in severe sepsis and septic shock. Am J Respir Crit Care Med. 2006; 174 1319-1326
- 2 Annane D, Sebille V, Bellissant E. Ger-Inf-05 Study Group . Effect of low doses of Corticosteroids in septic shock patients with or without early acute respiratory distress syndrome. Crit Care Med. 2006; 34 22-30
- 3 Annane D, Sebille V, Charpentier C. et al . Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002; 288 862-871
- 4 Annane D, Sébille V, Troché G, Raphaël J C, Gajdos P, Bellissant E. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA. 2000; 283 1038-1045
- 5 Bollaert P E, Charpentier C, Levy B. et al . Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med. 1998; 26 645-650
- 6 Briegel J, Forst H, Haller M. et al . Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, singlecenter study. Crit Care Med. 1999; 27 723-732
- 7 Chawla K, Kupfer Y, Tessler S. Hydrocortisone reverses refractory septic shock. Crit Care Med. 1999; 27 A33
- 8 Confalonieri M, Urbino R, Potena A. et al . Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study. Am J Respir Crit Care Med. 2005; 171 242-248
- 9 Eklund A, Leppaniemi A, Kemppainen E, Pettila V. Vasodilatory shock in severe acute pancreatitis without sepsis: is there any place for hydrocortisone treatment?. Acta Anaesthesiol Scand. 2005; 49 379-384
- 10 Halonen J, Halonen P, Järvinen O. et al . Corticosteroids for the prevention of atrial fibrillation after cardiac surgery. A randomized controlled trial. JAMA. 2007; 297 1562-1567
- 11 Hoen S, Mazoit J X, Asehnoune K. et al . Hydrocortisone increases the sensitivity to alpha1-adrenoceptor stimulation in humans following hemorrhagic shock. Crit Care Med. 2005; 33 2737-2743
- 12 Keh D, Boehnke T, Weber-Carstens S. et al . Immunologic and hemodynamic effects of „low dose” hydrocortisone in septic shock: a double-blind, randomized, placebo-controlled, crossover study. Am J Respir Crit Care Med. 2003; 167 512-520
- 13 Kilger E, Weis F, Briegel J. et al . Stress doses of hydrocortisone reduce severe systemic inflammatory response syndrome and improve early outcome in a risk group of patients after cardiac surgery. Crit Care Med. 2003; 31 1068-1074
- 14 Lipiner-Friedmann D, Sprung C L, Laterre P F. et al, Corticus Study Group . Adrenal function in sepsis: The retrospective Corticus cohort study. Crit Care Med. 2007; 35 1012-1018
- 15 Meduri G U, Golden E, Freire A X. et al . Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest. 2007; 131 954-963
- 16 Meduri G U, Headley A S, Golden E. et al . Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial. JAMA. 1998; 280 159-165
- 17 Meduri G U, Marik P E, Chrousos G P. et al . Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature. Intensive Care Med. 2008; 34 61-69
- 18 Meduri G U, Tolley E A, Chrousos G P, Stentz F. Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am J Respir Crit Care Med. 2002; 165 983-991
- 19 Muller C A, Vogeser M, Belyaev O. et al . Role of endogenous glucocorticoid metabolism in human acute pancreatitis. Crit Care Med. 2006; 34 1060-1066
- 20 Oppert M, Reinicke A, Graf K J. et al . Plasma cortisol levels before and during „low-dose” hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock. Intensive Care Med. 2000; 26 1747-1755
- 21 Oppert M, Schindler R, Husung C. et al . Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med. 2005; 33 2457-2464
- 22 Sprung C L, Annane D, Keh D. et al, CORTICUS Study Group . Hydrocortisone therapy for patients with septic shock. N Engl J Med. 2008; 358 111-124
- 23 Steinberg K P, Hudson L D, Goodman R B. et al . National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Efficacy and safety of Corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med. 2006; 354 1671-1684
- 24 Weis F, Kilger E, Beiras-Fernandez A. et al . Association between vasopressor dependence and early outcome in patients after cardiac surgery. Anaesthesia. 2006; 61 938-942
1 Herrn Prof. Dr. Dr. h. c. Klaus Peter zum 70. Geburtstag gewidmet.
Dr. med. Patrick Möhnle
Klinik für Anästhesiologie der Universität
München
Marchioninistr. 15
81377 München
Phone: 089/7095-3410
Fax: 089/7095-8886
Email: patrick.moehnle@med.uni-muenchen.de