Thorac Cardiovasc Surg 1979; 27(4): 227-230
DOI: 10.1055/s-0028-1096250
Copyright © 1979 by Georg Thieme Verlag

Hemofiltration during Extracorporeal Circulation (ECC)

J. Darup, N. Bleese, P. Kalmar, G. Lutz, H. Pokar, M.-J. Polonius
  • Department of Cardiovascular Surgery and Experimental Cardiology, University Hospital Eppendorf, Hamburg, West Germany
Further Information

Publication History

Publication Date:
11 December 2008 (online)

Summary

In cardiac surgery hemofiltration can be used:

  1. to balance fluids during ECC, especially in long-term perfusion;

  2. to carry out open heart procedures in patients with terminal renal insufficiency;

  3. to treat acute hyperkalemia.

The model of the 12.5 by 4.5 cm DIAFILTERTM* and the mode of operation are described. The compounds of the ultrafiltrate (UF) are identical with that of plasma water. Particles with a molecular weight of less than 50,000 can pass freely across the filtration membrane. The filtration capacity is 100 cc/min UF (Q blood: 300 cc/min, pressure across the membrane 600 mm Hg and hematokrit (Hkt) 25%).

The technical details of operation are explained. Its general use as well as its simplicity is demonstrated in 10 patients.